Is Your Multivitamin Going to Kill You?
Is Your Multivitamin Really Helping—or Harming You?
A recent 2024 JAMA article claims no mortality benefit from multivitamin use, but the study's flawed design raises significant doubts. Researchers combined data from three distinct cohorts with inconsistent surveys and methodologies, making it impossible to draw definitive conclusions. While one timepoint suggested a negligible 4% increase in mortality risk, later analysis found no significant differences. The study’s poor data quality leaves its conclusions shaky at best.
In contrast, the COSMOS study offers more robust findings. This large-scale trial involved over 20,000 participants, with a subgroup of 5,000 undergoing detailed cognitive assessments. Remarkably, even using a basic multivitamin like Centrum, researchers observed significant improvements in global cognition and episodic memory over two years. This suggests that even small doses of essential nutrients can benefit brain health, especially when studied rigorously.
Multivitamins in Clinical Practice
Dr. Kara Fitzgerald emphasizes a personalized approach to supplementation. While multivitamins can serve as a general safety net—especially for children or individuals with limited diets—she often opts for targeted nutrient prescriptions based on testing. Multivitamins can fill gaps but shouldn't replace a diet rich in whole foods and tailored interventions.
What Does This Mean for You?
While not all multivitamins are created equal, high-quality formulations backed by rigorous research can provide meaningful health benefits. Before starting any supplement, consult with a healthcare professional to determine what your body truly needs.
Update from Kara Fitzgerald, on 2024-09-05Source